Seraphina Do you need to have compatible blood types to get married?
Since hemolytic disease of newborns is caused by incompatible blood types between husband and wife, does everyone have to marry someone with the same blood type? Experts say there is no evidence that people need to have the same blood type to get married. Blood type incompatibility between husband and wife is very common, so neonatal hemolytic disease is also very common. However, this disease can generally be detected and treated in time, and almost all can be cured. It will not affect the future of the child. healthy cause impact.
According to reports, although fetus The mother's body relies on the mother to supply nutrients, but there is a "placental barrier" between the mother and the fetus. This barrier can protect the blood of mother and fetus from "mutual exchange." But there are still a few baby Red blood cells will leak into the maternal circulation, resulting in the production of antibodies, and a small amount of the mother's blood will enter the fetus. After the child is born, the blood with antibodies from the mother in the baby's body will be metabolized and exhausted within a certain period of time, and the child will soon return to normal.
Mothers with type O and babies with type A are most susceptible to the disease
It is understood that there are two main causes of neonatal hemolytic disease: ABO blood group system incompatibility and Rh blood group system incompatibility. In our country, the most common one is ABO blood group system incompatibility. Most mothers of children with ABO hemolytic disease have type O blood, and most babies have type A or type B blood.
ABO hemolytic disease usually occurs in the second child, but it may also occur in the first child. If a mother with type O blood (universal recipient) has been transfused with blood type A or B or AB before giving birth, or has a history of miscarriage (the mother's birth canal is damaged and the aborted fetus' blood enters the body), the mother will be "sensitized" and produce anti-A or B antibodies. Then even the first child may develop hemolytic disease of the newborn. Ms. Han had been pregnant before, but due to work, she had an induced abortion, which resulted in anti-A antibodies being produced in her body, so her daughter who was born later developed severe hemolysis.
It is understood that the chance and severity of neonatal hemolytic disease increase with the number of parities. In addition, some female Although this is the first childbirth, there are substances similar to ABO blood types in nature, which can enter the human body through various channels and produce antibodies, causing the baby to develop hemolytic disease of the newborn.
This disease cannot be prevented but it can be cured
“neonatal hemolytic disease in clinical It is very common, but generally there are no serious consequences. Especially with the advancement of medical technology in recent years, there have almost never been dangerous cases. ”Dr. Liang said.
It is understood that the symptoms of the disease range from mild to severe. Babies often develop jaundice within 24 hours or the next day after birth, and it worsens rapidly. Because the mother's antibodies in the baby's body are depleted every day, the symptoms will gradually improve. Severe babies will appear anemia , and even "kernicterus", that is, bilirubin encephalopathy, is caused by a substance called bilirubin produced after the destruction of red blood cells entering the brain. This is the most serious consequence. Generally, people with ABO blood type incompatibility will not have such results.
Please pay more attention when type O wife and non-type O husband have children.
It is understood that because the selection of the baby's genetic material cannot be controlled, there is currently no good way to prevent the disease. The doctor reminds women with blood types A, B or AB, and the wife has blood type O and has a history of miscarriage or blood transfusion. You should think about this issue when you are pregnant and seek medical advice if necessary.
At the same time, a survey also showed that 30% of pregnancies in China have blood group incompatibility, and the incidence rate of neonatal hemolytic hemolytic is 11.9%, but there are few serious cases.
