Chronic inflammation of cervical tissue with squamous metaplasia

Chronic inflammation of cervical tissue with squamous metaplasia is a pathological change caused by chronic inflammation of the cervix, which may be caused by human papillomavirus infection, bacterial infection, mechanical stimulation and other factors. It usually presents with symptoms such as abnormal leucorrhea and contact bleeding. It is recommended to confirm the diagnosis through cervical cytology and HPV testing, and follow the doctor’s instructions to take anti-infective treatment, physical therapy or surgical intervention.

1. Human papillomavirus infection

Persistent infection with high-risk HPV is the main cause, which can lead to abnormal differentiation of cervical epithelial cells. Patients may experience symptoms such as bleeding after intercourse and irregular vaginal bleeding. HPV typing testing is required. After diagnosis, local treatment with interferon suppositories, Baofukang suppositories and other drugs can be used as directed by the doctor. Cervical conization can be performed if necessary. Regular cervical TCT and HPV screening are crucial.

2. Bacterial vaginosis

Mixed infections caused by pathogenic bacteria such as Gardnerella may aggravate the inflammatory response and are often accompanied by gray-white fishy-smelling leucorrhea. The diagnosis can be confirmed through vaginal secretion examination. Treatment requires the use of metronidazole vaginal effervescent tablets, clindamycin phosphate vaginal cream and other antibacterial drugs as directed by the doctor, as well as lactic acid bacteria vaginal capsules to adjust the balance of the bacterial flora.

3. Mechanical stimulation factors

Repeated abortions, childbirth injuries, or long-term use of intrauterine devices may cause repeated damage to the cervical mucosa. It is recommended to avoid unnecessary uterine cavity operations. For those who have already suffered damage, recombinant human epidermal growth factor gel can be applied topically to promote repair. Antibiotic treatment is required when combined with infection.

4. Hormone level disorders

Abnormal estrogen levels may affect the process of cervical columnar epithelial migration, which is common in perimenopausal women. Six items of sex hormones need to be tested, and if necessary, estrogen and progesterone should be supplemented under the guidance of a doctor. Traditional Chinese medicine preparations such as Kuntai Capsules may help regulate endocrine, but contraindications to medication need to be ruled out.

5. Immune dysfunction

Diabetic patients or those who use immunosuppressants for a long time are prone to persistent cervical inflammation. To control underlying diseases and enhance immunity, immune modulators such as Pidotimod oral liquid and spleen aminopeptide oral freeze-dried powder must be strictly followed, but the medication instructions of specialists must be strictly followed.

Patients should keep their vulva clean and dry and avoid using irritating vaginal washes. It is recommended to choose pure cotton underwear and change it daily, and use condoms during sex to reduce the risk of cross-infection. Increase the intake of high-quality protein and vitamins in the diet and limit high-sugar foods. Carry out regular gynecological examinations and cervical cancer screenings every 6-12 months. If you have blood-stained leucorrhea or worsening lower abdominal pain, you need to be followed up in time. Quitting smoking and maintaining a regular schedule can help improve local microcirculation and promote the resolution of inflammation.